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Specifications
- Host Species
- Mouse
- Antibody Isotype
- IgG1
- Clone
- 222709
- Species Reactivity
- Human
- Immunogen
- Insect ovarian cell line T. ni-derived recombinant human TACE/ADAM17. Pro18-Asn671 (predicted) Accession Number P78536
- Conjugate
- Unconjugated
Applications
- Application Notes
- ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.5-2.0 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4144 - DCABY-4328
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Target
- Alternative Names
- ADAM17; ADAM metallopeptidase domain 17; CSVP; TACE; NISBD; ADAM18; CD156B; disintegrin and metalloproteinase domain-containing protein 17; TNF-alpha convertase; snake venom-like protease; TNF-alpha converting enzyme; ADAM metallopeptidase domain 18; tumo
- Entrez Gene ID
- 6868
- UniProt ID
- B2RNB2
References
Feldinger, K; Generali, D; et al. ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer. ONCOTARGET 5:6633-6646(2014).
Yu, CC; Tsai, LL; et al. miR145 Targets the SOX9/ADAM17 Axis to Inhibit Tumor-Initiating Cells and IL-6-Mediated Paracrine Effects in Head and Neck Cancer. CANCER RESEARCH 73:3425-3440(2013).