1中国科学院微生物研究所，北京100101
2中国科学院生命科学与生物技术局工业生物技术与产业化处
北京100864
于波，曾艳，姜旭，等.聚合级L一乳酸的非粮生物质发酵研究进展.生物工程学报，2013, 29(4): 411-421.
Yu B, Zeng Y, Jiang X, et al. Trends in polymer-grade L-lactic acid fermentation by non-food biomass. Chin J Biotech, 2013
29(4): 411-421.
摘要:乳酸在化工、医药和食品加工等领域有着广泛的用途。随着聚乳酸产业的兴起，对聚合级L一乳酸的需求量也不断增加。开发低成本的非粮生物质乳酸发酵工艺、实现发酵一分离辐合是降低聚合级L一乳酸成本、摆脱原料价格不断上涨压力的技术趋势。文中简要综述了近2}3年使用非粮生物质发酵生产聚合级L一乳酸的技术进展，并对未来乳酸发酵工艺作了展望。
关键词:L一乳酸，非粮生物质，发酵一分离耦合
Trends in polymer-grade L一lactic acid fermentation by
non一food biomass
Bo Yul, Yan Zeng2, Xu Jiangl, Limin Wangl, and Yanhe Mal
l Institute ofMicrobiology, ChineseAcademy ofSciences, Being 100101, China
2 Division of Industrial Bio-Tech Research and Development, Bureau of Life Science and Biotechnology，Chinese Academy of Sciences,
Being 100864, China
Abstract: Lactic acid has a wide range of uses in the chemical, pharmaceutical and food industry. With rapid
development of poly (lactic acid) industry, the demand for polymer-grade L-lactic acid is continuously increasing
Developing low-cost, non-food-biomass-lactic-acid fermentation process and the fermentation-separation coupled
technology are trends to reduce polymer-grade L-lactic acid production cost. This review summarized the most recent
advances in low-cost L-lactic acid fermentation based on the use of non-food biomass, followed by addressing the key issue
that might be strategically important for future development of polymer-grade L-lactic acid production in industry
Keywords: L-lactic acid, non-food biomass, fermentation-separation coupled technology
